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Rhodes, Christopher

One or more keywords matched the following items that are connected to Rhodes, Christopher

Item Type	Name
Academic Article	A novel regulatory mechanism for trimeric GTP-binding proteins in the membrane and secretory granule fractions of human and rodent beta cells.
Academic Article	Insulin-secreting non-islet cells are resistant to autoimmune destruction.
Academic Article	Acute stimulation with long chain acyl-CoA enhances exocytosis in insulin-secreting cells (HIT T-15 and NMRI beta-cells).
Academic Article	Chronic exposure to free fatty acid reduces pancreatic beta cell insulin content by increasing basal insulin secretion that is not compensated for by a corresponding increase in proinsulin biosynthesis translation.
Academic Article	How is the insulin content regulated in nondiabetic hyperinsulinaemic, insulin resistant states? Study of spontaneously hypertensive rats.
Academic Article	Synaptotagmin III isoform is compartmentalized in pancreatic beta-cells and has a functional role in exocytosis.
Academic Article	Cysteine string protein (CSP) is an insulin secretory granule-associated protein regulating beta-cell exocytosis.
Academic Article	A distinct difference in the metabolic stimulus-response coupling pathways for regulating proinsulin biosynthesis and insulin secretion that lies at the level of a requirement for fatty acyl moieties.
Academic Article	Changes in cytoplasmic ATP concentration parallels changes in ATP-regulated K+-channel activity in insulin-secreting cells.
Academic Article	A low-affinity Ca2+-dependent association of calmodulin with the Rab3A effector domain inversely correlates with insulin exocytosis.
Academic Article	Ca2+-dependent dephosphorylation of kinesin heavy chain on beta-granules in pancreatic beta-cells. Implications for regulated beta-granule transport and insulin exocytosis.
Academic Article	Glucose-induced translational control of proinsulin biosynthesis is proportional to preproinsulin mRNA levels in islet beta-cells but not regulated via a positive feedback of secreted insulin.
Academic Article	Syncollin inhibits regulated corticotropin secretion from AtT-20 cells through a reduction in the secretory vesicle population.
Academic Article	A role for the malonyl-CoA/long-chain acyl-CoA pathway of lipid signaling in the regulation of insulin secretion in response to both fuel and nonfuel stimuli.
Academic Article	Fluorescent cargo proteins in pancreatic beta-cells: design determines secretion kinetics at exocytosis.
Academic Article	10th EASD/JDRF Oxford Workshop. What is a beta-cell and can we improve it?
Academic Article	Impact of defined matrix interactions on insulin production by cultured human beta-cells: effect on insulin content, secretion, and gene transcription.
Academic Article	Regulated autophagy controls hormone content in secretory-deficient pancreatic endocrine beta-cells.
Academic Article	Insulin regulates glucagon-like peptide-1 secretion from the enteroendocrine L cell.
Academic Article	Glucagon-like peptide-1 regulates proliferation and apoptosis via activation of protein kinase B in pancreatic INS-1 beta cells.
Academic Article	[Biogenesis of the insulin secretion granule].
Academic Article	The mitochondrial citrate/isocitrate carrier plays a regulatory role in glucose-stimulated insulin secretion.
Academic Article	Arf nucleotide binding site opener [ARNO] promotes sequential activation of Arf6, Cdc42 and Rac1 and insulin secretion in INS 832/13 ß-cells and rat islets.
Academic Article	The balance between proinsulin biosynthesis and insulin secretion: where can imbalance lead?
Academic Article	Protein farnesylation-dependent Raf/extracellular signal-related kinase signaling links to cytoskeletal remodeling to facilitate glucose-induced insulin secretion in pancreatic beta-cells.
Academic Article	Newly synthesized proinsulin/insulin and stored insulin are released from pancreatic B cells predominantly via a regulated, rather than a constitutive, pathway.
Academic Article	Effect of human lymphoblastoid interferon on insulin synthesis and secretion in isolated human pancreatic islets.
Academic Article	Co-secretion of carboxypeptidase H and insulin from isolated rat islets of Langerhans.
Academic Article	PKC-dependent stimulation of exocytosis by sulfonylureas in pancreatic beta cells.
Academic Article	Long-term biochemical changes in the islets of Langerhans in mice following infection with encephalomyocarditis virus.
Academic Article	Molecular insights into insulin action and secretion.
Academic Article	Diazoxide attenuates glucose-induced defects in first-phase insulin release and pulsatile insulin secretion in human islets.
Academic Article	Direct imaging shows that insulin granule exocytosis occurs by complete vesicle fusion.
Academic Article	Intragranular targeting of syncollin, but not a syncollinGFP chimera, inhibits regulated insulin exocytosis in pancreatic beta-cells.
Academic Article	Effects of glucose and D-3-hydroxybutyrate on human pancreatic islet cell function.
Academic Article	Rab3A effector domain peptides induce insulin exocytosis via a specific interaction with a cytosolic protein doublet.
Academic Article	ß1 integrin is a crucial regulator of pancreatic ß-cell expansion.
Academic Article	Monomethylated-adenines potentiate glucose-induced insulin production and secretion via inhibition of phosphodiesterase activity in rat pancreatic islets.
Academic Article	Dominant-negative PKC-epsilon impairs apical actin remodeling in parallel with inhibition of carbachol-stimulated secretion in rabbit lacrimal acini.
Academic Article	Subcellular resolution mapping of endogenous cytokine secretion by nano-plasmonic-resonator sensor array.
Academic Article	The dynamic plasticity of insulin production in ß-cells.
Academic Article	Biosynthesis and storage of insulin.
Academic Article	Characterization of Signaling Pathways Associated with Pancreatic ß-cell Adaptive Flexibility in Compensation of Obesity-linked Diabetes in db/db Mice.
Academic Article	A fluorescent timer reporter enables sorting of insulin secretory granules by age.
Grant	Metabolic Control of Insulin Exocytosis
Grant	Central Control of Pancreatic Islet Function
Grant	Western Region Islet Study Group

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